Modified clot waveform analysis (CWA)

نویسندگان

چکیده

凝固波形解析(clot waveform analysis: CWA)には,活性化部分トロンボプラスチン時間(activated partial thromboplastin time: APTT),プロトロンビン時間(prothrombin PT),トロンビン時間(thrombin TT)などがあり,エビデンスが集積されつつある.また,生理的な凝固能を評価するために,種々の修正CWAが開発されつつある.修正CWAには,CWA-PT/APTT,CWA-希釈PT(small amount TF induced FIX activation: sTF/FIXa),CWA-希釈TT,global coagulation and fibrinolysis testなどがある.CWA-sTF/FIXaはpeak heightの増加で過凝固状態を,peak timeの延長で血小板減少を示唆する.CWA-希釈TTはトロンビンバーストを反映し,global testは,凝固能に加え線溶能も評価できる.

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ژورنال

عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis

سال: 2023

ISSN: ['0915-7441', '1880-8808']

DOI: https://doi.org/10.2491/jjsth.34.36